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HSF1-Controlled and Age-Associated Chaperone Capacity in Neurons and Muscle Cells of C. elegans

Protein stability under changing conditions is of vital importance for the cell and under the control of a fine-tuned network of molecular chaperones. Aging and age-related neurodegenerative diseases are directly associated with enhanced protein instability. Employing C. elegans expressing GFP-tagge...

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Detalles Bibliográficos
Autores principales: Kern, Andreas, Ackermann, Bianca, Clement, Albrecht M., Duerk, Heike, Behl, Christian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797298/
https://www.ncbi.nlm.nih.gov/pubmed/20052290
http://dx.doi.org/10.1371/journal.pone.0008568