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HSF1-Controlled and Age-Associated Chaperone Capacity in Neurons and Muscle Cells of C. elegans
Protein stability under changing conditions is of vital importance for the cell and under the control of a fine-tuned network of molecular chaperones. Aging and age-related neurodegenerative diseases are directly associated with enhanced protein instability. Employing C. elegans expressing GFP-tagge...
Autores principales: | Kern, Andreas, Ackermann, Bianca, Clement, Albrecht M., Duerk, Heike, Behl, Christian |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797298/ https://www.ncbi.nlm.nih.gov/pubmed/20052290 http://dx.doi.org/10.1371/journal.pone.0008568 |
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