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Mechanisms of c-Myc Degradation by Nickel Compounds and Hypoxia
Nickel (Ni) compounds have been found to cause cancer in humans and animal models and to transform cells in culture. At least part of this effect is mediated by stabilization of hypoxia inducible factor (HIF1a) and activating its downstream signaling. Recent studies reported that hypoxia signaling m...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797325/ https://www.ncbi.nlm.nih.gov/pubmed/20046830 http://dx.doi.org/10.1371/journal.pone.0008531 |