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Parameter Identifiability and Redundancy in a General Class of Stochastic Carcinogenesis Models

BACKGROUND: Heidenreich et al. (Risk Anal 1997 17 391–399) considered parameter identifiability in the context of the two-mutation cancer model and demonstrated that combinations of all but two of the model parameters are identifiable. We consider the problem of identifiability in the recently devel...

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Detalles Bibliográficos
Autores principales: Little, Mark P., Heidenreich, Wolfgang F., Li, Guangquan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797326/
https://www.ncbi.nlm.nih.gov/pubmed/20046831
http://dx.doi.org/10.1371/journal.pone.0008520