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Avicin D, a Plant Triterpenoid, Induces Cell Apoptosis by Recruitment of Fas and Downstream Signaling Molecules into Lipid Rafts

Avicins, a family of triterpene electrophiles originally identified as potent inhibitors of tumor cell growth, have been shown to be pleiotropic compounds that also possess antioxidant, anti-mutagenic, and anti-inflammatory activities. We previously showed that Jurkat cells, which express a high lev...

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Detalles Bibliográficos
Autores principales: Xu, Zhi-Xiang, Ding, Tian, Haridas, Valsala, Connolly, Fiona, Gutterman, Jordan U.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797328/
https://www.ncbi.nlm.nih.gov/pubmed/20046832
http://dx.doi.org/10.1371/journal.pone.0008532