LDLR Expression and Localization Are Altered in Mouse and Human Cell Culture Models of Alzheimer's Disease

BACKGROUND: Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most common form of dementia. The major molecular risk factor for late-onset AD is expression of the ε-4 allele of apolipoprotein E (apoE), the major cholesterol transporter in the brain. The low-density lipopr...

Descripción completa

Detalles Bibliográficos
Autores principales: Abisambra, Jose F., Fiorelli, Tina, Padmanabhan, Jaya, Neame, Peter, Wefes, Inge, Potter, Huntington
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797391/
https://www.ncbi.nlm.nih.gov/pubmed/20049331
http://dx.doi.org/10.1371/journal.pone.0008556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797391/
https://www.ncbi.nlm.nih.gov/pubmed/20049331
http://dx.doi.org/10.1371/journal.pone.0008556

Ejemplares similares