Structure of the hDmc1-ssDNA Filament Reveals the Principles of Its Architecture

In eukaryotes, meiotic recombination is a major source of genetic diversity, but its defects in humans lead to abnormalities such as Down's, Klinefelter's and other syndromes. Human Dmc1 (hDmc1), a RecA/Rad51 homologue, is a recombinase that plays a crucial role in faithful chromosome segr...

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Detalles Bibliográficos
Autores principales: Okorokov, Andrei L., Chaban, Yuriy L., Bugreev, Dmitry V., Hodgkinson, Julie, Mazin, Alexander V., Orlova, Elena V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797393/
https://www.ncbi.nlm.nih.gov/pubmed/20062530
http://dx.doi.org/10.1371/journal.pone.0008586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797393/
https://www.ncbi.nlm.nih.gov/pubmed/20062530
http://dx.doi.org/10.1371/journal.pone.0008586

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