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MRP2 and GSTP1 polymorphisms and chemotherapy response in advanced non-small cell lung cancer

PURPOSE: The level of drug metabolism and drug transport is correlated with the sensitivity of cancer cells towards platinum-based chemotherapy. We hypothesize that genetic polymorphisms in metabolising enzymes gene GSTP1 (glutathione S-transferase P1), and MRP2 (multidrug resistance-associated prot...

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Detalles Bibliográficos
Autores principales: Sun, Ning, Sun, Xinchen, Chen, Baoan, Cheng, Hongyan, Feng, Jifeng, Cheng, Lu, Lu, Zuhong
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797421/
https://www.ncbi.nlm.nih.gov/pubmed/19568750
http://dx.doi.org/10.1007/s00280-009-1046-1