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MRP2 and GSTP1 polymorphisms and chemotherapy response in advanced non-small cell lung cancer
PURPOSE: The level of drug metabolism and drug transport is correlated with the sensitivity of cancer cells towards platinum-based chemotherapy. We hypothesize that genetic polymorphisms in metabolising enzymes gene GSTP1 (glutathione S-transferase P1), and MRP2 (multidrug resistance-associated prot...
Autores principales: | Sun, Ning, Sun, Xinchen, Chen, Baoan, Cheng, Hongyan, Feng, Jifeng, Cheng, Lu, Lu, Zuhong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797421/ https://www.ncbi.nlm.nih.gov/pubmed/19568750 http://dx.doi.org/10.1007/s00280-009-1046-1 |
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