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Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer

The phosphatidylinositol 3-kinase (PI3K) pathway is a critical signal transduction pathway that regulates multiple cellular functions. Aberrant activation of this pathway has been identified in a wide range of cancers. Several pathway components including AKT, PI3K and mTOR represent potential thera...

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Detalles Bibliográficos
Autores principales: Knowles, Margaret A., Platt, Fiona M., Ross, Rebecca L., Hurst, Carolyn D.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797439/
https://www.ncbi.nlm.nih.gov/pubmed/20013032
http://dx.doi.org/10.1007/s10555-009-9198-3