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Ischaemic preconditioning improves proteasomal activity and increases the degradation of δPKC during reperfusion

AIMS: The response of the myocardium to an ischaemic insult is regulated by two highly homologous protein kinase C (PKC) isozymes, δ and εPKC. Here, we determined the spatial and temporal relationships between these two isozymes in the context of ischaemia/reperfusion (I/R) and ischaemic preconditio...

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Detalles Bibliográficos
Autores principales: Churchill, Eric N., Ferreira, Julio C., Brum, Patricia C., Szweda, Luke I., Mochly-Rosen, Daria
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797452/
https://www.ncbi.nlm.nih.gov/pubmed/19820255
http://dx.doi.org/10.1093/cvr/cvp334