CENPA overexpression promotes genome instability in pRb-depleted human cells

BACKGROUND: Aneuploidy is a hallmark of most human cancers that arises as a consequence of chromosomal instability and it is frequently associated with centrosome amplification. Functional inactivation of the Retinoblastoma protein (pRb) has been indicated as a cause promoting chromosomal instabilit...

Descripción completa

Detalles Bibliográficos
Autores principales: Amato, Angela, Schillaci, Tiziana, Lentini, Laura, Di Leonardo, Aldo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797498/
https://www.ncbi.nlm.nih.gov/pubmed/20003272
http://dx.doi.org/10.1186/1476-4598-8-119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797498/
https://www.ncbi.nlm.nih.gov/pubmed/20003272
http://dx.doi.org/10.1186/1476-4598-8-119

Ejemplares similares