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Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease
The excitotoxin quinolinic acid (QUIN) is synthesized through the kynurenine pathway (KP) by activated monocyte lineage cells. QUIN is likely to play a role in the pathogenesis of several major neuroinflammatory diseases including Alzheimer's disease (AD). The presence of reactive astrocytes, a...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797503/ https://www.ncbi.nlm.nih.gov/pubmed/20003262 http://dx.doi.org/10.1186/1742-2094-6-36 |