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Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease

The excitotoxin quinolinic acid (QUIN) is synthesized through the kynurenine pathway (KP) by activated monocyte lineage cells. QUIN is likely to play a role in the pathogenesis of several major neuroinflammatory diseases including Alzheimer's disease (AD). The presence of reactive astrocytes, a...

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Detalles Bibliográficos
Autores principales:	Ting, Ka Ka, Brew, Bruce J, Guillemin, Gilles J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797503/ https://www.ncbi.nlm.nih.gov/pubmed/20003262 http://dx.doi.org/10.1186/1742-2094-6-36

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