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Evidence for an association of HLA-DRB1*15 and DRB1*09 with leprosy and the impact of DRB1*09 on disease onset in a Chinese Han population

BACKGROUND: Human leukocyte antigens (HLAs) have been proposed to modulate the immune response to Mycobacterium leprae. The association of HLA-DRB1 with leprosy has been reported in several populations, but not in a Chinese population. METHODS: The polymerase chain reaction-sequence-specific oligonu...

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Detalles Bibliográficos
Autores principales: Zhang, Furen, Liu, Hong, Chen, Shumin, Wang, Changyuan, Zhu, Chuanfu, Zhang, Lin, Chu, Tongsheng, Liu, Dianchang, Yan, Xiaoxiao, Liu, Jianjun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797507/
https://www.ncbi.nlm.nih.gov/pubmed/20003324
http://dx.doi.org/10.1186/1471-2350-10-133