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Co-Orientation of Replication and Transcription Preserves Genome Integrity
In many bacteria, there is a genome-wide bias towards co-orientation of replication and transcription, with essential and/or highly-expressed genes further enriched co-directionally. We previously found that reversing this bias in the bacterium Bacillus subtilis slows replication elongation, and we...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797598/ https://www.ncbi.nlm.nih.gov/pubmed/20090829 http://dx.doi.org/10.1371/journal.pgen.1000810 |