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LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor

RATIONALE: Compounds that activate the 5-HT(2A) receptor, such as lysergic acid diethylamide (LSD), act as hallucinogens in humans. One notable exception is the LSD congener lisuride, which does not have hallucinogenic effects in humans even though it is a potent 5-HT(2A) agonist. LSD and other hall...

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Detalles Bibliográficos
Autores principales: Halberstadt, Adam L., Geyer, Mark A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797624/
https://www.ncbi.nlm.nih.gov/pubmed/19937319
http://dx.doi.org/10.1007/s00213-009-1718-x