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Intracranial Administration of P Gene siRNA Protects Mice from Lethal Chandipura Virus Encephalitis
BACKGROUND: In parts of India, Chandipura Virus (CHPV) has emerged as an encephalitis causing pathogen in both epidemic and sporadic forms. This pediatric disease follows rapid course leading to 55–75% mortality. In the absence of specific treatment, effectiveness of RNA interference (RNAi) was eval...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797643/ https://www.ncbi.nlm.nih.gov/pubmed/20062542 http://dx.doi.org/10.1371/journal.pone.0008615 |