Structure of the HCMV UL16-MICB Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse NKG2D Ligands

The activating immunoreceptor NKG2D promotes elimination of infected or malignant cells by cytotoxic lymphocytes through engagement of stress-induced MHC class I-related ligands. The human cytomegalovirus (HCMV)-encoded immunoevasin UL16 subverts NKG2D-mediated immune responses by retaining a select...

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Detalles Bibliográficos
Autores principales: Müller, Steffen, Zocher, Georg, Steinle, Alexander, Stehle, Thilo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797645/
https://www.ncbi.nlm.nih.gov/pubmed/20090832
http://dx.doi.org/10.1371/journal.ppat.1000723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797645/
https://www.ncbi.nlm.nih.gov/pubmed/20090832
http://dx.doi.org/10.1371/journal.ppat.1000723

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