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DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort

BACKGROUND: As dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibilit...

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Detalles Bibliográficos
Autores principales: Vázquez-Higuera, José Luis, Sánchez-Juan, Pascual, Rodríguez-Rodríguez, Eloy, Mateo, Ignacio, Pozueta, Ana, Frank, Ana, Sastre, Isabel, Valdivieso, Fernando, Berciano, José, Bullido, María J, Combarros, Onofre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797783/
https://www.ncbi.nlm.nih.gov/pubmed/19995442
http://dx.doi.org/10.1186/1471-2350-10-129