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DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort
BACKGROUND: As dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibilit...
Autores principales: | Vázquez-Higuera, José Luis, Sánchez-Juan, Pascual, Rodríguez-Rodríguez, Eloy, Mateo, Ignacio, Pozueta, Ana, Frank, Ana, Sastre, Isabel, Valdivieso, Fernando, Berciano, José, Bullido, María J, Combarros, Onofre |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797783/ https://www.ncbi.nlm.nih.gov/pubmed/19995442 http://dx.doi.org/10.1186/1471-2350-10-129 |
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