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Direct rosiglitazone action on steroidogenesis and proinflammatory factor production in human granulosa-lutein cells
BACKGROUND: Ovarian granulosa cells are the predominant source of estradiol and progesterone biosynthesis in vivo. Rosiglitazone, a synthetic agonist of the peroxisome proliferator-activated receptor gamma (PPAR gamma), is applied as the treatment of insulin resistance including women with PCOS. The...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797791/ https://www.ncbi.nlm.nih.gov/pubmed/20003221 http://dx.doi.org/10.1186/1477-7827-7-147 |