ATP-Sensitive K(+) Channel Mediates the Zinc Switch-Off Signal for Glucagon Response During Glucose Deprivation

OBJECTIVE: The intraislet insulin hypothesis proposes that glucagon secretion during hypoglycemia is triggered by a decrease in intraislet insulin secretion. A more recent hypothesis based on in vivo data from hypoglycemic rats is that it is the decrease in zinc cosecreted with insulin from β-cells,...

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Detalles Bibliográficos
Autores principales: Slucca, Michela, Harmon, Jamie S., Oseid, Elizabeth A., Bryan, Joseph, Robertson, R. Paul
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797913/
https://www.ncbi.nlm.nih.gov/pubmed/19808893
http://dx.doi.org/10.2337/db09-1098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797913/
https://www.ncbi.nlm.nih.gov/pubmed/19808893
http://dx.doi.org/10.2337/db09-1098

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