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ATP-Sensitive K(+) Channel Mediates the Zinc Switch-Off Signal for Glucagon Response During Glucose Deprivation
OBJECTIVE: The intraislet insulin hypothesis proposes that glucagon secretion during hypoglycemia is triggered by a decrease in intraislet insulin secretion. A more recent hypothesis based on in vivo data from hypoglycemic rats is that it is the decrease in zinc cosecreted with insulin from β-cells,...
Autores principales: | Slucca, Michela, Harmon, Jamie S., Oseid, Elizabeth A., Bryan, Joseph, Robertson, R. Paul |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797913/ https://www.ncbi.nlm.nih.gov/pubmed/19808893 http://dx.doi.org/10.2337/db09-1098 |
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