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Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells

OBJECTIVE: Carbohydrate-responsive element-binding protein (ChREBP) is a transcription factor that has been shown to regulate carbohydrate metabolism in the liver and pancreatic β-cells in response to elevated glucose concentrations. Because few genes have been identified so far as bona fide ChREBP-...

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Detalles Bibliográficos
Autores principales: Noordeen, Nafeesa A., Khera, Tarnjit K., Sun, Gao, Longbottom, E. Rebecca, Pullen, Timothy J., da Silva Xavier, Gabriela, Rutter, Guy A., Leclerc, Isabelle
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797916/
https://www.ncbi.nlm.nih.gov/pubmed/19833882
http://dx.doi.org/10.2337/db08-0868