Association of Metformin, Elevated Homocysteine, and Methylmalonic Acid Levels and Clinically Worsened Diabetic Peripheral Neuropathy

OBJECTIVE: The severity of peripheral neuropathy in diabetic patients varies for unclear reasons. Long-term use of metformin is associated with malabsorption of vitamin B(12) (cobalamin [Cbl]) and elevated homocysteine (Hcy) and methylmalonic acid (MMA) levels, which may have deleterious effects on...

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Detalles Bibliográficos
Autores principales: Wile, Daryl J., Toth, Cory
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797962/
https://www.ncbi.nlm.nih.gov/pubmed/19846797
http://dx.doi.org/10.2337/dc09-0606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797962/
https://www.ncbi.nlm.nih.gov/pubmed/19846797
http://dx.doi.org/10.2337/dc09-0606

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