Onset dynamics of type A botulinum neurotoxin-induced paralysis

Experimental studies have demonstrated that botulinum neurotoxin serotype A (BoNT/A) causes flaccid paralysis by a multi-step mechanism. Following its binding to specific receptors at peripheral cholinergic nerve endings, BoNT/A is internalized by receptor-mediated endocytosis. Subsequently its zinc...

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Detalles Bibliográficos
Autores principales: Lebeda, Frank J., Adler, Michael, Erickson, Keith, Chushak, Yaroslav
Formato: Texto
Lenguaje:English
Publicado: Springer US 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798021/
https://www.ncbi.nlm.nih.gov/pubmed/18551355
http://dx.doi.org/10.1007/s10928-008-9087-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798021/
https://www.ncbi.nlm.nih.gov/pubmed/18551355
http://dx.doi.org/10.1007/s10928-008-9087-3

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