Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers

We focus on unique roles of miR-200c in breast, ovarian, and endometrial cancers. Members of the miR-200 family target ZEB1, a transcription factor which represses E-cadherin and other genes involved in polarity. We demonstrate that the double negative feedback loop between miR-200c and ZEB1 is func...

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Detalles Bibliográficos
Autores principales: Cochrane, Dawn R., Howe, Erin N., Spoelstra, Nicole S., Richer, Jennifer K.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798671/
https://www.ncbi.nlm.nih.gov/pubmed/20049172
http://dx.doi.org/10.1155/2010/821717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798671/
https://www.ncbi.nlm.nih.gov/pubmed/20049172
http://dx.doi.org/10.1155/2010/821717

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