Cargando…

Chk1 Haploinsufficiency Results in Anemia and Defective Erythropoiesis

BACKGROUND: Erythropoiesis is a highly regulated and well-characterized developmental process responsible for providing the oxygen transport system of the body. However, few of the mechanisms involved in this process have been elucidated. Checkpoint Kinase 1 (Chk1) is best known for its role in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Boles, Nathan C., Peddibhotla, Sirisha, Chen, Alice J., Goodell, Margaret A., Rosen, Jeffrey M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798715/
https://www.ncbi.nlm.nih.gov/pubmed/20052416
http://dx.doi.org/10.1371/journal.pone.0008581