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Chk1 Haploinsufficiency Results in Anemia and Defective Erythropoiesis
BACKGROUND: Erythropoiesis is a highly regulated and well-characterized developmental process responsible for providing the oxygen transport system of the body. However, few of the mechanisms involved in this process have been elucidated. Checkpoint Kinase 1 (Chk1) is best known for its role in the...
Autores principales: | Boles, Nathan C., Peddibhotla, Sirisha, Chen, Alice J., Goodell, Margaret A., Rosen, Jeffrey M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798715/ https://www.ncbi.nlm.nih.gov/pubmed/20052416 http://dx.doi.org/10.1371/journal.pone.0008581 |
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