Type I Interferon Induction Is Detrimental during Infection with the Whipple's Disease Bacterium, Tropheryma whipplei

Macrophages are the first line of defense against pathogens. Upon infection macrophages usually produce high levels of proinflammatory mediators. However, macrophages can undergo an alternate polarization leading to a permissive state. In assessing global macrophage responses to the bacterial agent...

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Detalles Bibliográficos
Autores principales: Al Moussawi, Khatoun, Ghigo, Eric, Kalinke, Ulrich, Alexopoulou, Lena, Mege, Jean-Louis, Desnues, Benoit
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798751/
https://www.ncbi.nlm.nih.gov/pubmed/20090833
http://dx.doi.org/10.1371/journal.ppat.1000722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798751/
https://www.ncbi.nlm.nih.gov/pubmed/20090833
http://dx.doi.org/10.1371/journal.ppat.1000722

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