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Anion-Sensitive Regions of L-Type CaV1.2 Calcium Channels Expressed in HEK293 Cells

L-type calcium currents (I(Ca)) are influenced by changes in extracellular chloride, but sites of anion effects have not been identified. Our experiments showed that CaV1.2 currents expressed in HEK293 cells are strongly inhibited by replacing extracellular chloride with gluconate or perchlorate. Va...

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Detalles Bibliográficos
Autores principales: Babai, Norbert, Kanevsky, Nataly, Dascal, Nathan, Rozanski, George J., Singh, Dhirendra P., Fatma, Nigar, Thoreson, Wallace B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798859/
https://www.ncbi.nlm.nih.gov/pubmed/20066046
http://dx.doi.org/10.1371/journal.pone.0008602