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A Statistical Method for the Detection of Alternative Splicing Using RNA-Seq

Deep sequencing of transcriptome (RNA-seq) provides unprecedented opportunity to interrogate plausible mRNA splicing patterns by mapping RNA-seq reads to exon junctions (thereafter junction reads). In most previous studies, exon junctions were detected by using the quantitative information of juncti...

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Detalles Bibliográficos
Autores principales: Wang, Liguo, Xi, Yuanxin, Yu, Jun, Dong, Liping, Yen, Laising, Li, Wei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798953/
https://www.ncbi.nlm.nih.gov/pubmed/20072613
http://dx.doi.org/10.1371/journal.pone.0008529