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A Statistical Method for the Detection of Alternative Splicing Using RNA-Seq
Deep sequencing of transcriptome (RNA-seq) provides unprecedented opportunity to interrogate plausible mRNA splicing patterns by mapping RNA-seq reads to exon junctions (thereafter junction reads). In most previous studies, exon junctions were detected by using the quantitative information of juncti...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798953/ https://www.ncbi.nlm.nih.gov/pubmed/20072613 http://dx.doi.org/10.1371/journal.pone.0008529 |