Quantitative Modeling of GRK-Mediated β2AR Regulation

We developed a unified model of the GRK-mediated β2 adrenergic receptor (β2AR) regulation that simultaneously accounts for six different biochemical measurements of the system obtained over a wide range of agonist concentrations. Using a single deterministic model we accounted for (1) GRK phosphoryl...

Descripción completa

Detalles Bibliográficos
Autores principales: Vayttaden, Sharat J., Friedman, Jacqueline, Tran, Tuan M., Rich, Thomas C., Dessauer, Carmen W., Clark, Richard B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798957/
https://www.ncbi.nlm.nih.gov/pubmed/20098494
http://dx.doi.org/10.1371/journal.pcbi.1000647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798957/
https://www.ncbi.nlm.nih.gov/pubmed/20098494
http://dx.doi.org/10.1371/journal.pcbi.1000647

Ejemplares similares