A Novel Method to Adjust Efficacy Estimates for Uptake of Other Active Treatments in Long-Term Clinical Trials

BACKGROUND: When rates of uptake of other drugs differ between treatment arms in long-term trials, the true benefit or harm of the treatment may be underestimated. Methods to allow for such contamination have often been limited by failing to preserve the randomization comparisons. In the Fenofibrate...

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Detalles Bibliográficos
Autores principales: Simes, John, Voysey, Merryn, O'Connell, Rachel, Glasziou, Paul, Best, James D., Scott, Russell, Pardy, Christopher, Byth, Karen, Sullivan, David R., Ehnholm, Christian, Keech, Anthony
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798963/
https://www.ncbi.nlm.nih.gov/pubmed/20072614
http://dx.doi.org/10.1371/journal.pone.0008580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798963/
https://www.ncbi.nlm.nih.gov/pubmed/20072614
http://dx.doi.org/10.1371/journal.pone.0008580

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