Intravenously Administered Alphavirus Vector VA7 Eradicates Orthotopic Human Glioma Xenografts in Nude Mice

BACKGROUND: VA7 is a neurotropic alphavirus vector based on an attenuated strain of Semliki Forest virus. We have previously shown that VA7 exhibits oncolytic activity against human melanoma xenografts in immunodeficient mice. The purpose of this study was to determine if intravenously administered...

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Detalles Bibliográficos
Autores principales: Heikkilä, Jari E., Vähä-Koskela, Markus J. V., Ruotsalainen, Janne J., Martikainen, Miika W., Stanford, Marianne M., McCart, J. Andrea, Bell, John C., Hinkkanen, Ari E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799335/
https://www.ncbi.nlm.nih.gov/pubmed/20066051
http://dx.doi.org/10.1371/journal.pone.0008603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799335/
https://www.ncbi.nlm.nih.gov/pubmed/20066051
http://dx.doi.org/10.1371/journal.pone.0008603

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