Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development

BACKGROUND: The homeodomain containing transcription factor Nkx2.2 is essential for the differentiation of pancreatic endocrine cells. Deletion of Nkx2.2 in mice leads to misspecification of islet cell types; insulin-expressing β cells and glucagon-expressing α cells are replaced by ghrelin-expressi...

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Detalles Bibliográficos
Autores principales: Anderson, Keith R, White, Peter, Kaestner, Klaus H, Sussel, Lori
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799404/
https://www.ncbi.nlm.nih.gov/pubmed/20003319
http://dx.doi.org/10.1186/1471-213X-9-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799404/
https://www.ncbi.nlm.nih.gov/pubmed/20003319
http://dx.doi.org/10.1186/1471-213X-9-65

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