Cargando…
Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development
BACKGROUND: The homeodomain containing transcription factor Nkx2.2 is essential for the differentiation of pancreatic endocrine cells. Deletion of Nkx2.2 in mice leads to misspecification of islet cell types; insulin-expressing β cells and glucagon-expressing α cells are replaced by ghrelin-expressi...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799404/ https://www.ncbi.nlm.nih.gov/pubmed/20003319 http://dx.doi.org/10.1186/1471-213X-9-65 |