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Mass action models versus the Hill model: An analysis of tetrameric human thymidine kinase 1 positive cooperativity

BACKGROUND: The Hill coefficient characterizes the extent to which an enzyme exhibits positive or negative cooperativity, but it provides no information regarding the mechanism of cooperativity. In contrast, models based on the equilibrium concept of mass action can suggest mechanisms of cooperativi...

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Detalles Bibliográficos
Autor principal: Radivoyevitch, Tomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799445/
https://www.ncbi.nlm.nih.gov/pubmed/20003201
http://dx.doi.org/10.1186/1745-6150-4-49