Altered Gene Expression and DNA Damage in Peripheral Blood Cells from Friedreich's Ataxia Patients: Cellular Model of Pathology

The neurodegenerative disease Friedreich's ataxia (FRDA) is the most common autosomal-recessively inherited ataxia and is caused by a GAA triplet repeat expansion in the first intron of the frataxin gene. In this disease, transcription of frataxin, a mitochondrial protein involved in iron homeo...

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Detalles Bibliográficos
Autores principales: Haugen, Astrid C., Di Prospero, Nicholas A., Parker, Joel S., Fannin, Rick D., Chou, Jeff, Meyer, Joel N., Halweg, Christopher, Collins, Jennifer B., Durr, Alexandra, Fischbeck, Kenneth, Van Houten, Bennett
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799513/
https://www.ncbi.nlm.nih.gov/pubmed/20090835
http://dx.doi.org/10.1371/journal.pgen.1000812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799513/
https://www.ncbi.nlm.nih.gov/pubmed/20090835
http://dx.doi.org/10.1371/journal.pgen.1000812

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