Acute Administration of Non-Classical Estrogen Receptor Agonists Attenuates Ischemia-Induced Hippocampal Neuron Loss in Middle-Aged Female Rats

BACKGROUND: Pretreatment with 17β-estradiol (E2) is profoundly neuroprotective in young animals subjected to focal and global ischemia. However, whether E2 retains its neuroprotective efficacy in aging animals, especially when administered after brain insult, is largely unknown. METHODOLOGY/PRINCIPA...

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Detalles Bibliográficos
Autores principales: Lebesgue, Diane, Traub, Michael, De Butte-Smith, Maxine, Chen, Christopher, Zukin, R. Suzanne, Kelly, Martin J., Etgen, Anne M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799530/
https://www.ncbi.nlm.nih.gov/pubmed/20062809
http://dx.doi.org/10.1371/journal.pone.0008642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799530/
https://www.ncbi.nlm.nih.gov/pubmed/20062809
http://dx.doi.org/10.1371/journal.pone.0008642

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