A New Target for Amyloid Beta Toxicity Validated by Standard and High-Throughput Electrophysiology

BACKGROUND: Soluble oligomers of amyloid beta (Aβ) are considered to be one of the major contributing factors to the development of Alzheimer's disease. Most therapeutic development studies have focused on toxicity directly at the synapse. METHODOLOGY/PRINCIPAL FINDINGS: Patch clamp studies det...

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Detalles Bibliográficos
Autores principales: Varghese, Kucku, Molnar, Peter, Das, Mainak, Bhargava, Neelima, Lambert, Stephen, Kindy, Mark S., Hickman, James J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799531/
https://www.ncbi.nlm.nih.gov/pubmed/20062810
http://dx.doi.org/10.1371/journal.pone.0008643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799531/
https://www.ncbi.nlm.nih.gov/pubmed/20062810
http://dx.doi.org/10.1371/journal.pone.0008643

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