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A New Target for Amyloid Beta Toxicity Validated by Standard and High-Throughput Electrophysiology
BACKGROUND: Soluble oligomers of amyloid beta (Aβ) are considered to be one of the major contributing factors to the development of Alzheimer's disease. Most therapeutic development studies have focused on toxicity directly at the synapse. METHODOLOGY/PRINCIPAL FINDINGS: Patch clamp studies det...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799531/ https://www.ncbi.nlm.nih.gov/pubmed/20062810 http://dx.doi.org/10.1371/journal.pone.0008643 |