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Blurring of High-Resolution Data Shows that the Effect of Intrinsic Nucleosome Occupancy on Transcription Factor Binding is Mostly Regional, Not Local

Genome wide maps of nucleosome occupancy in yeast have recently been produced through deep sequencing of nuclease-protected DNA. These maps have been obtained from both crosslinked and uncrosslinked chromatin in vivo, and from chromatin assembled from genomic DNA and nucleosomes in vitro. Here, we a...

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Detalles Bibliográficos
Autores principales: Goh, Wee Siong, Orlov, Yuriy, Li, Jingmei, Clarke, Neil D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799660/
https://www.ncbi.nlm.nih.gov/pubmed/20098497
http://dx.doi.org/10.1371/journal.pcbi.1000649