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Delivery of Factor VIII Gene into Skeletal Muscle Cells Using Lentiviral Vector

PURPOSE: This study was designed to investigate whether transduction of lentiviral vectors (LV) carrying human coagulation factor VIII (hFVIII) cDNA into skeletal muscle could increase circulating hFVIII concentrations. MATERIALS AND METHODS: A LV containing bacterial LacZ gene as a control or human...

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Detalles Bibliográficos
Autores principales: Jeon, Hyun Jeong, Oh, Tae Keun, Kim, Oak Hee, Kim, Seung Taik
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799978/
https://www.ncbi.nlm.nih.gov/pubmed/20046514
http://dx.doi.org/10.3349/ymj.2010.51.1.52