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Identifying differentially methylated genes using mixed effect and generalized least square models

BACKGROUND: DNA methylation plays an important role in the process of tumorigenesis. Identifying differentially methylated genes or CpG islands (CGIs) associated with genes between two tumor subtypes is thus an important biological question. The methylation status of all CGIs in the whole genome can...

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Detalles Bibliográficos
Autores principales: Sun, Shuying, Yan, Pearlly S, Huang, Tim HM, Lin, Shili
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800121/
https://www.ncbi.nlm.nih.gov/pubmed/20003206
http://dx.doi.org/10.1186/1471-2105-10-404