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Vaccination of Mice with Salmonella Expressing VapA: Mucosal and Systemic Th1 Responses Provide Protection against Rhodococcus equi Infection

Conventional vaccines to prevent the pneumonia caused by Rhodococcus equi have not been successful. We have recently demonstrated that immunization with Salmonella enterica Typhimurium expressing the VapA antigen protects mice against R. equi infection. We now report that oral vaccination of mice wi...

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Detalles Bibliográficos
Autores principales: Oliveira, Aline F., Ruas, Luciana P., Cardoso, Silvia A., Soares, Sandro G., Roque-Barreira, Maria-Cristina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800180/
https://www.ncbi.nlm.nih.gov/pubmed/20072623
http://dx.doi.org/10.1371/journal.pone.0008644