A Duchenne Muscular Dystrophy Gene Hot Spot Mutation in Dystrophin-Deficient Cavalier King Charles Spaniels Is Amenable to Exon 51 Skipping

BACKGROUND: Duchenne muscular dystrophy (DMD), which afflicts 1 in 3500 boys, is one of the most common genetic disorders of children. This fatal degenerative condition is caused by an absence or deficiency of dystrophin in striated muscle. Most affected patients have inherited or spontaneous deleti...

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Detalles Bibliográficos
Autores principales: Walmsley, Gemma L., Arechavala-Gomeza, Virginia, Fernandez-Fuente, Marta, Burke, Margaret M., Nagel, Nicole, Holder, Angela, Stanley, Rachael, Chandler, Kate, Marks, Stanley L., Muntoni, Francesco, Shelton, G. Diane, Piercy, Richard J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800183/
https://www.ncbi.nlm.nih.gov/pubmed/20072625
http://dx.doi.org/10.1371/journal.pone.0008647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800183/
https://www.ncbi.nlm.nih.gov/pubmed/20072625
http://dx.doi.org/10.1371/journal.pone.0008647

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