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Genetic and Molecular Analyses of PEG10 Reveal New Aspects of Genomic Organization, Transcription and Translation

The paternally expressed gene PEG10 is a retrotransposon derived gene adapted through mammalian evolution located on human chromosome 7q21. PEG10 codes for at least two proteins, PEG10-RF1 and PEG10-RF1/2, by -1 frameshift translation. Overexpression or reinduced PEG10 expression was seen in maligna...

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Detalles Bibliográficos
Autores principales: Lux, Heike, Flammann, Heiko, Hafner, Mathias, Lux, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800197/
https://www.ncbi.nlm.nih.gov/pubmed/20084274
http://dx.doi.org/10.1371/journal.pone.0008686