Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase

Telomerase, the essential enzyme that maintains telomere length, contains two core components, TERT and TR. Early studies in yeast and mouse showed that loss of telomerase leads to phenotypes only after several generations, due to telomere shortening. However, recent studies have suggested additiona...

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Detalles Bibliográficos
Autores principales: Vidal-Cardenas, Sofia L., Greider, Carol W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800220/
https://www.ncbi.nlm.nih.gov/pubmed/19850716
http://dx.doi.org/10.1093/nar/gkp855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800220/
https://www.ncbi.nlm.nih.gov/pubmed/19850716
http://dx.doi.org/10.1093/nar/gkp855

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